Massive Perivillous Fibrin Deposition Maternal Floor Infarction

Katzman pj genest dr.

Massive perivillous fibrin deposition maternal floor infarction.

Mpfd is a rare disorder characterized by deposition of fibrinoid material in the intervillous space leading to atrophy of the engulfed villi. Massive perivillous fibrin deposition mpvfd and maternal floor infarction mfi are pregnancy complications of unknown aetiology characterised by extensive deposition of fibrin either within the intervillous space or primarily within and around the basal plate. Am j obstet gynecol 1990 163 935 8. Maternal floor infarction is a similar process in which the fibrinoid material is confined to the basal villi.

Maternal floor infarction mfi is a poorly understood placental lesion reportedly associated with intrauterine growth restriction iugr and recurrence. In this study of mfi and the related placental disorder massive perivillous fibrin deposition mfd semiquantitative histologic criteria for these diagnoses are defined and rates of iugr and. Maternal floor infarction and massive perivillous fibrin deposition. The association of maternal floor infarction of the placenta with adverse perinatal outcome.

Histological definitions association with intrauterine fetal growth restriction and risk of recurrence. Massive deposition of intervillous fibrin that entrap the villi of the basal plate extending to a thickness of at least 3 mm may be accompanied by massive perivillous fibrin deposition associated with recurrent abortions stillbirth fetal growth restriction or neurologic impairment seen in 0 09 0 5 of placentas. Pediatr dev pathol 5 2. In this study of mfi and the related placental disorder massive perivillous fibrin deposition mfd semiquantitative histologic criteria for the.

Massive perivillous fibrin deposition mpfd and maternal floor infarction mfi of the placenta are rare related conditions associated with poor perinatal outcome including antepartum stillbirth. Massive perivillous fibrin deposition. Maternal floor infarction and massive perivillous fibrin deposition. Objective massive perivillous fibrin deposition mpfd and maternal floor infarction mfi are related placental lesions often associated with fetal death and fetal growth restriction.

Maternal floor infarction mfi and massive perivillous fibrin deposition mpvfd are pathologically overlapping placental disorders with characteristic gross and shared light microscopic features of excessive perivillous deposition of fibrinoid material.